Well the difference is simple. As the name suggest, Radio Telescope is not like a normal Optical telescope which is much larger version of binoculars or spy glass.Ok, you asked for it. Now tell me the difference b/w a regular telescope (Ladakh) & radio telescope.
Radio telescopes does use radio waves to sketch up images whereas the optical telescope (like the one in plan at Ladakh) uses visual images instead.
Optical telescopes does comprise of a large glass to collect light from source, whereas Radio telescope does have a large antenna or an array of antennas to collect reflected radio waves. In other words Radio telescopes are large RADAR.