A region having the highest haplotype indicates that those genes originated there? How? I doubt this is a known fact, but I could be wrong. Please share with me any research article that explains how and why this genetic marker moving from place A to B will show diversity in A?
It is the other way round. Diversity shows direction, instead of direction telling about diversity.
More haplotype diversity of a genetic component in location A as compared to B; will show that the component in A is older than B.
Shared and Unique Components of Human Population Structure and Genome-Wide Signals of Positive Selection in South Asia
...Combining our results with other available genome-wide data, we show that Indian populations are characterized by two major ancestry components, one of which is spread at comparable frequency and haplotype diversity in populations of South and West Asia and the Caucasus. The second component is more restricted to South Asia and accounts for more than 50% of the ancestry in Indian populations. Haplotype diversity associated with these South Asian ancestry components is significantly higher than that of the components dominating the West Eurasian ancestry palette. Modeling of the observed haplotype diversities suggests that both Indian ancestry components are older than the purported Indo-Aryan invasion 3,500 YBP...
....If the k5 light green ancestry component (Figure 2B) originated from a recent gene flow event (for example by a demic diffusion model) with a single center of dispersal where the underlying alleles emerged, then one would expect different levels of associated haplotypic diversity to suggest the point of origin of the migration.....
.....we found that haplotypic diversity of this ancestry component is much greater than that of those dominating in Europe (k4, depicted in dark blue) and the Near East (k3, depicted in light blue), thus pointing to an older age of the component and/or long-term higher effective population size (i.e. indigenous evolution of people).....
.....our current results indicate that the often debated episode of South Asian prehistory, the putative Indo-Aryan migration 3,500 years ago falls well within the limits of our haplotype-based approach (mini12,500 BYP). We found no regional diversity differences associated with k5 at K = 8. Thus, regardless of where this component was from (the Caucasus, Near East, Indus Valley, or Central Asia), its spread to other regions must have occurred well before our detection limits at 12,500 years. Accordingly, the introduction of k5 to South Asia cannot be explained by recent gene flow, such as the hypothetical Indo-Aryan migration...
Both k5 and k6 ancestry components that dominate genetic variation in South Asia at K = 8 demonstrate much greater haplotype diversity than those that predominate in West Eurasia. This pattern is indicative of a more ancient demographic history and/or a higher long-term effective population size underlying South Asian genome variation compared to that of West Eurasia...
South Asian genetic diversity is 2nd in the world, next only to Africa, mainly due to long periods of indigenous development of lineages and with complex population structure where one can see the different caste and tribal populations.
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New research debunks Aryan invasion theory - India - DNA
....According to Prof Singh, Dr Chaubey, and Dr Kumarasamy Thangaraj, another member of the team, the findings disprove the caste theory prevailing in India. interestingly, the team found that instead of aryan invasion, it was indians who moved from the subcontinent to europe. "That's the reason behind the findings of the same genetic traits in eurasiain regions," said Dr Thangaraj, senior scientist, CCMB....
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Genomic view on the peopling of India http://www.investigativegenetics.com/content/pdf/2041-2223-3-20.pdf
No support for the Aryan invasion
Even though there is a continued debate on the Aryan migration into India, detectable gene flow from west Eurasia has been shown by many studies[13,16,23,24,30-32,44,51,53].
Interestingly, we have detected gene flow from the west prior to the Aryan invasion[30,32].
There is now universal agreement that various Indian populations share a common late Pleistocene
maternal and paternal ancestry, along with detectable east and west Eurasian ancestries [31,54].
Using hundreds of thousands of autosomal markers, we illustrated that the Indian populations have two major distinct ancestry components; one restricted to southern India, the second one restricted to the northern region of India [30,32].
It is noteworthy that both of the ancestry components show higher haplotypic diversity than those predominant
in west Eurasia [32].
This rejects the idea of an Aryan invasion/migration and suggests an ancient demographic history and/or higher long-term larger effective population size in India than in west Eurasia......
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Recently, archaeological evidence supporting the early peopling of India was discovered in the Kurnool district of Andhra Pradesh, one of the southern Indian states [9,10].
This study shows that the country was inhabited by modern humans before and after the Toba eruptionaround 74,000 YBP.
The evidence is in the form of stone tools. The stone tools of this study most likely resemble contemporaneous Homo sapiens technologies in Africa.
Further, a partial cranium recovered from Narmada Basin was dated back to around 300,000 to 250,000 YBP [11,12]....
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Thangaraj, Metspalu and others conclude that the shared genetic affinity between the ANI component of northern India and west Eurasia was dated atleast 12500 YBP and thus definitely prior to the supposed Aryan migration.
Regards,
Virendra