Wuhan Coronavirus Thread

Is coronavirus a biological warfare agent released by China?

  • yes

    Votes: 105 91.3%
  • no

    Votes: 10 8.7%

  • Total voters
    115

Chandragupt Maurya

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Govt is not declaring Rapid Antigen Test (RAT) positive numbers, only RT-PCR positive patients are being reported. Same for number of people died, if RT PCR positive pt, only then he/she will be on the list otherwise no. And that means very less numbers (almost 10 times) of reported cases and deaths
I don’t think Rapid Antigen test is confirmatory it can give false positive results RT PCR is 99% accurate
 

Kumata

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More, almost 5-10 times you can consider because no RAT positive cases are reported in the positive list and most of the cases are diagnosed on the basis of Rapid kit only.
Noobs Question - Rapid antigen would come positive only if person is infected and have recovered....right!!!
 

IndianYonko

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Everyone stay home as much as possible.. Take care of Old ones.

Kids(i.e. Students in colleges and schools)

-- Don't wase your time. Utilize it as much as possible. Learn new skills. Enhance your current skills. After lockdown things will get tough and this will give you a headstart.

Job Holders
-- help others, red pill as much people as you can. Also keep your skill updated. Pray to your favourite God that you don't lose your job.

Pls don't try to game the situation. no point getting over pessimistic; we have only limited control on situation. Lets give our best and hope for best

In this nation everyone is oversmart; No point over thinking.
 

Chandragupt Maurya

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There is difference between screening tests and Confirmatory test after screening you need to confirm the diagnosis
 

sajobajo

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@VIP sir, can you let us know how many breakthrough cases are we seeing which have really poor outcomes?

https://timesofindia.indiatimes.com...aking-2-vaccine-jabs/articleshow/82075952.cms

News like the above is not helping confidence in the vaccine. Already I have heard so many people around me getting infected, hospitalized and even passed away after getting infected post Jab-1. How many days post dose-1 I am not sure, but ranges from 3 days to 20 days for sure. Just now got to know of a case wherein someone I know needs an O2 bed for their mother, she had received the first dose on 15th March, ie, a full month back. Hence my earlier question to you about your experience with people with first dose.
 

another_armchair

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@VIP sir, can you let us know how many breakthrough cases are we seeing which have really poor outcomes?

https://timesofindia.indiatimes.com...aking-2-vaccine-jabs/articleshow/82075952.cms

News like the above is not helping confidence in the vaccine. Already I have heard so many people around me getting infected, hospitalized and even passed away after getting infected post Jab-1. How many days post dose-1 I am not sure, but ranges from 3 days to 20 days for sure. Just now got to know of a case wherein someone I know needs an O2 bed for their mother, she had received the first dose on 15th March, ie, a full month back. Hence my earlier question to you about your experience with people with first dose.
Hi, please do share whether your friends mother took Covishield or Covaxin.

Wish her a speedy recovery. Tough times ahead.
 

Knowitall

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More, almost 5-10 times you can consider because no RAT positive cases are reported in the positive list and most of the cases are diagnosed on the basis of Rapid kit only.
Govt needs to be transparent with numbers only when people understand the true scale of the situation will they actually start being cautious again due to fear and stay indoors.

Right now the thinking is its bad but not that bad when the situation is worse actually.

In their stupidity to save their image they are letting the populace remain complacent.
 

shade

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Govt needs to be transparent with numbers only when people understand the true scale of the situation will they actually start being cautious again due to fear and stay indoors.

Right now the thinking is its bad but not that bad when the situation is worse actually.

In their stupidity to save their image they are letting the populace remain complacent.
Right now it is

>"Corona is a conspiracy, it is a myth, nothing like this exists"

once sarkar drops the real numbers they will go into panik mode and start buying up all the masks, hand sanitizers and daily use items.
 

Knowitall

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Right now it is

>"Corona is a conspiracy, it is a myth, nothing like this exists"

once sarkar drops the real numbers they will go into panik mode and start buying up all the masks, hand sanitizers and daily use items.
Karne do bhai at least they wil stay in.

One of the biggest reasons why the first lockdown was such a success was due to the fact that janta was deadly scared of covid so scared people were even afraid of doctors everyone was very alert and people in communities were acting together to protect each other.

Hiding numbers to save their face will blow up on the face of govt worse Indian public is in this false sense of sab changa si mood due to information being controlled.

Govt needs to show the real numbers and modi needs to come and talk to the nation. Have a very candid talk with everyone explain the situation and consequences only then will people understand.
 

VIP

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I don’t think Rapid Antigen test is confirmatory it can give false positive results RT PCR is 99% accurate
Rapid test has very high specificity, if you're RAT positive, then there's 99% chances that you're infected. Compared to RT PCR, that has low specificity but higher sensitivity(70%) than RAT(50%). So, if you're RAT negative, doesn't mean you're negative, you might be RT PCR positive and even if you're RT PCR negative, there's high chance that you're HRCT positive. The HRCT Thorax has the highest sensitivity and specificity.
 

VIP

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@VIP sir, can you let us know how many breakthrough cases are we seeing which have really poor outcomes?

https://timesofindia.indiatimes.com...aking-2-vaccine-jabs/articleshow/82075952.cms

News like the above is not helping confidence in the vaccine. Already I have heard so many people around me getting infected, hospitalized and even passed away after getting infected post Jab-1. How many days post dose-1 I am not sure, but ranges from 3 days to 20 days for sure. Just now got to know of a case wherein someone I know needs an O2 bed for their mother, she had received the first dose on 15th March, ie, a full month back. Hence my earlier question to you about your experience with people with first dose.
If you're vaccinated, doesn't mean you won't get the infection, you might get infection but the severity will be very less. For example, polio vaccine, if you have taken polio vaccine (IPV not OPV), you will still get polio infection but the severity like damaging your muscles won't happen, only symptoms like diarrhoea will be there and you will recover in no time and you will obviously won't know what actually caused the diarrhoea as it's very common.

After getting 2nd dose of vaccine, it will take 1-2 months to develop proper immunity against this chini fk, only 1 dose doesn't give you proper protection.
 

here2where

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My prev post was deleted for unexplained reasons.... never mind..... happenings in next few days/weeks will substantiate my deleted post.

Some ppl wait till their ass gets bitten...science over superstition...

Covid-19: 2nd largest akhada exits Kumbh after Nirwani head dies

https://timesofindia.indiatimes.com...er-nirwani-head-dies/articleshow/82092811.cms

Buts it’s already too late .... virus cluster is dispersing and will spread further, infecting innocents who had nothing to do with the superstition...

Karnataka govt asks Kumbh Mela returnees to isolate themselves and undergo COVID test

https://economictimes.indiatimes.co...d-undergo-covid-test/articleshow/82082235.cms

Too late iam afraid.
 

Kumata

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We had a 600 million capacity vaccine plant staying idle in Tamil nadu all this time 😳 .... govt now approaching bharat biotech to make covaxin there

https://theprint.in/health/modi-gov...e-covaxin-in-tamil-nadus-chengalpattu/640266/
Typical first world babu problem.. No body got the under-table money so not functional...Since it was started by UPA , NDA would give a damm anyways..

Now that shit is thru roof & they have found it...hopefully it will start by the time half of india is dead... Other day i was reading a artcile where author was justifying death of Old / compromised immune system due to covid since that will govt reduce the expense on health care....
 

johnq

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Asthma drug brings hope for COVID-19 treatment
A steroid commonly used in asthma inhalers has the potential to prevent severe COVID-19 symptoms. It could treat the illness early on and help to reduce pressure on hospitals.

A common asthma medication that can be used at home might be an effective treatment for early COVID-19 in adults, according to a study published in The Lancet medical journal.

University of Oxford researchers found that patients who took the drug budesonide when their first COVID-19 symptoms started were less likely to need urgent medical care or hospitalization, and had a shorter recovery time. It also reduced the chance of persistent symptoms and fever.

The randomized controlled trial involved 146 adults within seven days of the onset of mild COVID-19 symptoms. Half of the participants inhaled budesonide twice a day until their symptoms resolved, and the other half received the usual care given based on age, gender and existing illnesses.

In the budesonide group, only one person needed urgent medical care, compared to 10 people in the group who received the standard care for COVID-19.

Another University of Oxford study that has yet to be peer reviewed also found that inhaled budesonide helped people who were at a higher risk of severe COVID-19 outcomes recover quicker.

"There's good biological plausibility" for why corticosteroids would work, Chloe Bloom, a senior clinical research fellow at Imperial College London's National Heart and Lung Institute, told DW. Bloom was not involved in the study.

Corticosteroids like dexamethasone are already being used effectively in hospitalized, severely ill COVID-19 patients. Bloom said researchers think it likely reduces the inflammation associated with severe COVID-19. Budesonide probably works in a similar way, but may be more localized.

Studies have also shown that the use of inhaled steroids in people with asthma and chronic obstructive pulmonary disease (COPD) reduced the receptor that allows Sars-CoV-2 into the lungs, said Bloom, and lab work has shown that inhaled steroids can possibly prevent virus replication.

Taking pressure off hospitals

The scientists said the research was inspired after reports of COVID-19 hospital emissions showed that patients with chronic respiratory disease were significantly underrepresented.

They hypothesized that the widespread use among these patients of inhaled glucocorticoids, a type of corticosteroid, was behind this trend.

The research investigated whether budesonide had the potential to reduce COVID-19 patients' need for emergency care, therefore minimizing pressure on hospitals.

"It is a widely available, low-cost medicine — which is relatively safe, which can be given to patients early in their COVID-19 illness," said Mona Bafadhel, one of the study's authors and an associate professor of respiratory medicine at the University of Oxford. "This would take pressure off healthcare systems."

Karl Lauterbach, a Social Democrat member of the German parliament and epidemiologist, said on Twitter that the study was a "game changer," in part because it identifies a potential early COVID-19 treatment that can be prescribed by a doctor.

While much research on treating COVID-19 so far has focused on patients who already have severe symptoms, this trial shows potential for earlier intervention.

"What is unique about this trial is that it also looks at people who are at quite low risk in terms of having serious effects from COVID-19," said Bloom.

Soumya Swaminathan, chief scientist at the World Health Organization, on Twitter called the results "encouraging," and called for more research in the field of outpatient COVID-19 treatment.

The trial had to be stopped early due to the UK's second lockdown and other factors — but an independent statistical review concluded that study outcome would not change with further participant enrollment.

What do corticosteroids do?

Corticosteroids are naturally produced in the body, but synthetic versions are used as an anti-inflammatory medicine to treat a range of inflammatory illnesses.

Listed by the World Health Organization as an essential medicine, they are often prescribed for people with asthma and other respiratory diseases in the form of an inhaler. They reduce inflammation and are seen as essential for controlling the condition.

Corticosteroids represent one of two main types of treatment for asthmatics. They are designed to prevent an asthma attack from occurring in the first place by reducing the base level of inflammation. The second type of treatment, bronchodilators, are designed to relax the muscles when an attack does happen.

While corticosteroids are readily available and inexpensive in some parts of the world, this is not always the case for low- and middle-income countries, where access to such drugs can be limited, according to the 2018 Global Asthma Report.
 

Spindrift

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Asthma drug brings hope for COVID-19 treatment
A steroid commonly used in asthma inhalers has the potential to prevent severe COVID-19 symptoms. It could treat the illness early on and help to reduce pressure on hospitals.

A common asthma medication that can be used at home might be an effective treatment for early COVID-19 in adults, according to a study published in The Lancet medical journal.

University of Oxford researchers found that patients who took the drug budesonide when their first COVID-19 symptoms started were less likely to need urgent medical care or hospitalization, and had a shorter recovery time. It also reduced the chance of persistent symptoms and fever.

The randomized controlled trial involved 146 adults within seven days of the onset of mild COVID-19 symptoms. Half of the participants inhaled budesonide twice a day until their symptoms resolved, and the other half received the usual care given based on age, gender and existing illnesses.

In the budesonide group, only one person needed urgent medical care, compared to 10 people in the group who received the standard care for COVID-19.

Another University of Oxford study that has yet to be peer reviewed also found that inhaled budesonide helped people who were at a higher risk of severe COVID-19 outcomes recover quicker.

"There's good biological plausibility" for why corticosteroids would work, Chloe Bloom, a senior clinical research fellow at Imperial College London's National Heart and Lung Institute, told DW. Bloom was not involved in the study.

Corticosteroids like dexamethasone are already being used effectively in hospitalized, severely ill COVID-19 patients. Bloom said researchers think it likely reduces the inflammation associated with severe COVID-19. Budesonide probably works in a similar way, but may be more localized.

Studies have also shown that the use of inhaled steroids in people with asthma and chronic obstructive pulmonary disease (COPD) reduced the receptor that allows Sars-CoV-2 into the lungs, said Bloom, and lab work has shown that inhaled steroids can possibly prevent virus replication.

Taking pressure off hospitals

The scientists said the research was inspired after reports of COVID-19 hospital emissions showed that patients with chronic respiratory disease were significantly underrepresented.

They hypothesized that the widespread use among these patients of inhaled glucocorticoids, a type of corticosteroid, was behind this trend.

The research investigated whether budesonide had the potential to reduce COVID-19 patients' need for emergency care, therefore minimizing pressure on hospitals.

"It is a widely available, low-cost medicine — which is relatively safe, which can be given to patients early in their COVID-19 illness," said Mona Bafadhel, one of the study's authors and an associate professor of respiratory medicine at the University of Oxford. "This would take pressure off healthcare systems."

Karl Lauterbach, a Social Democrat member of the German parliament and epidemiologist, said on Twitter that the study was a "game changer," in part because it identifies a potential early COVID-19 treatment that can be prescribed by a doctor.

While much research on treating COVID-19 so far has focused on patients who already have severe symptoms, this trial shows potential for earlier intervention.

"What is unique about this trial is that it also looks at people who are at quite low risk in terms of having serious effects from COVID-19," said Bloom.

Soumya Swaminathan, chief scientist at the World Health Organization, on Twitter called the results "encouraging," and called for more research in the field of outpatient COVID-19 treatment.

The trial had to be stopped early due to the UK's second lockdown and other factors — but an independent statistical review concluded that study outcome would not change with further participant enrollment.

What do corticosteroids do?

Corticosteroids are naturally produced in the body, but synthetic versions are used as an anti-inflammatory medicine to treat a range of inflammatory illnesses.

Listed by the World Health Organization as an essential medicine, they are often prescribed for people with asthma and other respiratory diseases in the form of an inhaler. They reduce inflammation and are seen as essential for controlling the condition.

Corticosteroids represent one of two main types of treatment for asthmatics. They are designed to prevent an asthma attack from occurring in the first place by reducing the base level of inflammation. The second type of treatment, bronchodilators, are designed to relax the muscles when an attack does happen.

While corticosteroids are readily available and inexpensive in some parts of the world, this is not always the case for low- and middle-income countries, where access to such drugs can be limited, according to the 2018 Global Asthma Report.
Dr. @VIP is salbutamol a bronchodilator?
 

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