According to sources in the region, officials have been warning neighbourhoods and mosques that ethnic minority Muslim families are being forced to hand in religious items including the Koran and prayer mats.
They face severe punishment if they are discovered.
According to
Radio Free Asia, reports have emerged from Kashgar, Hotan and other regions of similar practices starting last week.
The spokesman for the exile World Uyghur Congress group, Dilxat Raxit said they received a notification saying that every single ethnic Uyghur must hand in any Islam-related items from their own home.
Copies of the Koran and related items must be handed into the government authorities, and there are will be notices being broadcast via WeChat, China's most popular social media app.